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• Understanding integration inhibitors for the treatment of HIV

  Dr. Afsaneh Motamed-Khorasani Pharmaceutical

  Integration of the retroviral genome into the host cell chromatin is the key step in the development of HIV disease. Blocking the integration of viral genome by integrase inhibitors is an attractive therapeutic strategy. Many integrase inhibitors were developed by rational drug design strategies. Many of these compounds proceeded for preclinical trials, but further clinical development was halted due to in vivo toxicity and nonspecificity of the drugs towards the target.

• TV viewer choices — Cool vs. quality

  Mitch Weinraub Communications

  For those who have spent years trying to make television pictures better (often with less bandwidth or fewer bits) and improve the quality of video services being delivered to pay customers homes, there seems to be a growing and disturbing trend.

• Denying the shot: Preventing prescription abuse at the pharmacy

  Jason Poquette Pharmaceutical

  As pharmacists we sometimes have to take a hockey goalie's approach to prescriptions we are asked to fill. Like my son's slapshots, they must be denied. Sometimes I feel bad about this. There are patients that have real problems with abusing medications. For some of them, there is nothing they would like more than to stop abusing. But they're addicted, and the addicted mind doesn't always respond in calm, rational, logical ways to problems.

• Practical applications for 3-D printing

  Nick Merrill Manufacturing

  Recently, NASA announced a plan to install a 3-D printer on the International Space Station. This will be a huge boon for astronauts, who would no longer have to wait for a resupply shuttle to bring critical replacement parts. While this is certainly a high-profile use for 3-D printing in remote areas, there are many remote locations on Earth where having an on-site printer could prove invaluable.

• What PQRS could look like in 2014

  Heidi Jannenga Healthcare Administration

  On July 19, the Centers for Medicare & Medicaid Services (CMS) published the 2014 Medicare Physician Fee Schedule (MPFS) Notice of Proposed Rulemaking (NPRM) in the Federal Register. According to this summary, most of the policies were open for comment until Sept. 6 and, pending final decisions (which hopefully will occur this month), will take effect Jan. 1, 2014.

• Challenges for today’s police chiefs: Establishing a foundation

  Rod Brown and Jim Pryde Law Enforcement, Defense & Security

  The responsibilities of a chief of police are becoming more complex with each passing day. The position always had its challenges — leading an organization in highly fluid environments, both internal and external, where the day can transform from standardized routine to chaotic crisis within mere moments.

• Leadership comes from experience

  Ray Haight Distribution & Warehousing

  Effective leadership in business, politics, family or any organization is critical to the success of that situation. I have seen and been involved in many situations at many trucking companies, nonprofit organizations and community efforts that would be succeeding with the addition of one missing element — effective leadership. Someone with dedication vision and a strong moral compass who walks the walk can fix almost any issue in any circumstance.

• 6 things managers should not talk about at work

  D. Albert Brannen Business Management, Services & Risk Management

  ​Managers have a special role for employers because they are legal agents. What they say, do and know can be attributed to their employer. Depending on the issue, employers can be strictly liable for the conduct of managers. Several laws come into play here, but there are certain things that managers should absolutely not talk about with employees or anyone else at work.

• 3 important steps for a running sustainable restaurant

  Becky Bicks Food & Beverage

  There is a growing emphasis on running sustainable businesses in a way that does not excessively deplete environmental, economic or societal resources. Sustainable businesses have little or minimal impact on local (or global) economies and environments. They are, in a sense, self-sustaining enterprises that operate by both taking from the world and giving back to it equally. One industry that has seen a particularly large increase in the focus on sustainability is the restaurant industry.

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