Sharee Ann Narciso
Articles by Sharee Ann Narciso
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New strategy aims to reduce transplant rejection
Tuesday, March 25, 2014UC San Francisco researchers have recently developed a two-pronged approach to the problem of organ transplantation rejections seen in recipients. The strategy aims to weaken specific immune responses that affect transplanted tissue.
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Trends and patterns in patient safety report to OPTN
Tuesday, January 21, 2014A comprehensive report on patient safety situations was sent to the Organ Procurement and Transplantation Network (OPTN) and is now accessible for public review. It was prepared at the request of both OPTN and the Operations and Safety Committee of the United Network for Organ Sharing (UNOS). The report is a summary of safety situations that were gathered through the UNet Improving Patient Safety (IPS) online portal and other sources.
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Challenges in machine perfusion preservation for DCD liver grafts
Tuesday, January 14, 2014There is a critical shortage in the number of available donor graft tissues, and donation after circulatory death (DCD) seems like the next best solution. It is vital to maintain the viability of organs until transplantation to ensure optimal graft survival and function. So far, the most commonly used preservation method in clinical practice is static cold storage. However, the risk of ischemic damage when performing DCD grafting jeopardizes the viability of organs during cold storage. Whether static cold storage is the best method to avoid organ deterioration from DCD is still unknown.
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Stalling organ rejection with atorvastatin
Monday, November 04, 2013A recent research paper in The Journal of Experimental Medicine discussed the framework of hypotheses being developed on the possible effects of statins on genes, leading to organ rejection after transplantation. This placed the spotlight on one of the most prescribed drugs in the world — atorvastatin, more commonly known as Lipitor. The drug resulted in longer survival for mice who had undergone transplantation compared to mice who did not receive treatment.